Pindakaas : wat is er bijzonder aan?

of Medicine, University of Louvain, 


At least ,given a bit of peanut butter to children before sleep  [after tooth-brushing!]
can help to prevent tooth caries [asheshet]
A most interesting fact is that in the seventies of the last century a Dutch physician Dr van Creveld was the first one to treat hemophilia with peanuts!
Many years later[in Israel] I discovered that the Chinese treated thrompocytopenia [not the same as hemophilia, but also causing bleedings] also  with peanuts.
I have seen in a  few patients with trombocytopenia good results with peanuts [the inner brown film / "shell' should also be eaten]

Can Eating Peanut Butter Cut Breast Cancer Risk in Later Life?

Regular consumption in childhood tied to 39 percent lower odds of benign breast disease by age 30



Friday, September 27, 2013 Benign breast disease -- noncancerous changes in the breast tissue -- is a risk factor for breast cancer, experts agree.

FRIDAY, Sept. 27 (HealthDay News) -- Eating peanut butter regularly as a preteen and teen girl appears to decrease the risk of developing benign breast disease as an adult, new research has found.

The researchers followed more than 9,000 females, beginning when they were aged 9 to 15 in 1996, until 2010, when they were young women. Eating peanut butter three days a week reduced the risk of developing benign breast disease by 39 percent, said Dr. Graham Colditz, senior study author.

"I think this gives us enormous hope there are strategies we could be following to help prevent breast cancer that we haven't capitalized on yet," said Colditz, the associate director for cancer prevention and control at the Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine, in St. Louis.

The study, published online Sept. 17 in Breast Cancer Research and Treatment, was funded by the Breast Cancer Research Foundation and the U.S. National Institutes of Health.

Benign breast disease is fairly common, and a known risk factor for breast cancer, Colditz said. Before menopause, "about one in four women have a benign lesion, confirmed by biopsy," he said. "It's very clear there is a strong link between the benign lesion and the subsequent risk of invasive breast cancer."

Depending on the characteristics of the benign lesion, he said, benign breast disease could increase breast cancer risk by threefold.

The study participants were part of a long-term, ongoing study on the health effects of diet and exercise in young people. They filled out questionnaires about their diet annually from 1996 until 2001, then four more times until 2010. They also reported if they had been diagnosed with benign breast disease. In all, 112 women said they had.

The researchers looked at foods with vegetable protein and vegetable fats, then focused on individual foods, including peanut butter, peanuts or other nuts, beans and corn.

A daily serving of any of these foods was linked with a 68 percent reduced risk of benign breast disease. At age 14, a daily serving of any of those foods was linked with a 66 percent lower risk of benign breast disease, and girls who had about three servings a week of peanut butter had a 39 percent lower risk.

The researchers found a link between eating peanut butter and lower breast disease risk, not a cause-and-effect relationship, and Colditz said he can't explain yet why the peanut butter seems protective.

"It could well be the protein," he said. In previous studies, the researchers have looked at other factors of a healthy diet, such as milk consumption, and their role in breast health. The peanut butter finding, he said, is strong, even when taking into account an overall healthy diet. "It's not something we can make go away," he said.

For now, Colditz said, the take-home message is for teens and preteens to substitute peanuts and peanut butter for less-healthy snacks such as cookies.

Another expert who reviewed the findings said the study is well done.

Dr. Steven Chen, an associate clinical professor of breast and endocrine surgery at the City of Hope Comprehensive Cancer Center, in Duarte, Calif., said that while lowering benign breast disease does lower breast cancer risk, many other factors increase breast cancer risk besides benign breast disease.

"It's always good to lower any risk [of breast cancer] you can, but whether peanut butter intake will have a major impact on developing breast cancer down the line, only time will tell," Chen said.

As for how to explain the link? "It's hard to say at this point," Chen said, adding that in countries where less meat is eaten, less breast cancer risk is reported. Based on the study findings, he said, teen girls and preteens "shouldn't avoid peanut butter and nuts if they are not allergic." Getting some protein through vegetables, which was also looked at in the study, is a good idea, too, he added.

SOURCES: Graham Colditz, M.D., Dr.P.H., associate director for cancer prevention and control, Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine, St. Louis; Steven Chen, M.D., associate clinical professor of breast and endocrine surgery, City of Hope Comprehensive Cancer Center, Duarte, Calif.; Sept. 17, 2013, Breast Cancer Research and Treatment, online

Copyright (c) 2013 
Double-blind Experiments on the Effect of a Peanut Extract on the
Bleeding Incidence in 92 Haemophiliacs*
Brit. med. J., 1967, 4, 453-456
It is the fate of patients afflicted with a life-long disease to be
subjected to therapeutic trials with new drugs or substances,
of which the possible impact on the underlying diseases is not
always apparent. A classical example is haemophilia ; a long
list of drugs has stirred a fleeting hope in patients affected
with this bleeding disorder when the new therapy coincides
with one of their cyclic symptomless periods.
The fortuitous observation by a haemophilic patient that
while consuming daily roasted peanuts the tenderness of an
acute knee haemarthrosis seemed to subside more rapidly has
focused attention to a possible beneficial factor in peanuts for
the treatment of haemophilia (Boudreaux et al., 1960). Largely
because of untimely and uncontrolled rumours in the lay press,
many haemophiliacs started experimenting on their own with
any available source of peanuts-for example, commercial
peanut butter, roasted and raw peanuts, or peanut flour.
The discovery of antifibrinolytic properties in peanuts,
together with a possibly increased fibrinolytic potential in
haemophiliacs (van Creveld et al., 1961), were thought to offer
a reasonable basis for further investigation; also because in
isolated studies a beneficial effect of peanuts or peanut extracts
on the bleeding incidence of haemophilic patients continued
to be reported (Briister, 1961 ; Bisordi, 1964). Unfortunately
these investigations were conducted in a limited number of
patients and with a variety of peanut preparations (raw or
roasted peanuts, peanut butter, peanut flour, or screw-pressed
extracted peanut meal) or peanut extracts (crude peanut oil,
hexane-extracted roasted peanuts, or 95 % ethanol extract of
peanut flour).
* Study organized with the kind co-operation of Belgian and Dutch
groups interested in the treatment of haemophilia. Belgium:
Louvain (M. Verstraete, J. Vermylen, and H. Van Itterbeek).
Netherlands: Amsterdam (S. van Creveld, I. A. Mochtar, and
J. Jonker), Leiden (E. A. Loeliger, A. Hensen, N. Fekkes, and J. J.
Veltkamp), Breda (C. P. M. Strybos), The Hague (C. H. W.
Leeksma), Zevenaar (F. B. M. Verhey).
t Associate Professor of Medicine, University of Louvain, Belgium.
tInvestigator ACF Amsterdam, Netherlands.
From the Laboratory of Blood Coagulation and Proteolysis, Department

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