How to treat a [sometimes very serious] Rota virus diarrhoea ?

A short introduction and summary.

Even in “developed” countries rota virus can cause serious diarrhoea and  is difficult to treat, at least that is what the medical text books write until now.

Wikipedia states: Treatment of acute rotavirus infection is nonspecific and involves management of symptoms and, most importantly, maintenance of hydration

This article i am sending you to show the opposite.

There is good and effective treatment for rota virus diarrhoea in addition to the important treatment with ORS [ search my yahoo group to read about ORS about which I wrote in length] and indeed I am surprised that nobody “edited” / added to the article on Wikipedia and corrected the word “non specific" If you don’t have some of the Brazilian plants "at hand" then one can get easily in Israel and Europe a  tincture of Tormentilla  and Nutmeg as aspice with which I have excellent experience in cases of severe diarrhoea [also when the diagnosis “rota” was made]

The main sentence in the article below:

 ..............Our results indicate that the extracts of Artocarpus integrifolia, Myristica fragrans and Spongias lutea  can be useful in the treatment of human diarrhea if the etiologic agent is a rotavirus.

Spondias,also called hogplum, is an excellent herbal antibiotic and I wish it was available in Israel.                                        Some patients ordered this on my suggestion.[...........The extracts of the leaf of Spondias mombin exhibited wide spectrum antibacterial effects comparable to those of Ampicillin and Gentamycin.]

Myristica fragrans is simple the same as nutmeg and many patients got telephone advise from me to use nutmeg for diarrhoea.[nutmeg is a “sam” so a very little bit should be used [pinch]] It is extremely useful!

If you want to see more about Spondias [or  want to order]

then look at :http://www.tropilab.com/tincture.html 

  and in general :  http://www.tropilab.com/index.html

Journal of Ethnopharmacology

Volume 99, Issue 3, 14 July 2005, Pages 403-407

  Cited By in Scopus (28)

Short communication

In vitro anti-rotavirus activity of some medicinal plants used in Brazil against diarrhea

J.L.S. Gonçalves^a, R.C. Lopes^b, D.B. Oliveira^c, S.S. Costa^c, M.M.F.S. Miranda^a, 1, M.T.V. Romanos^a, N.S.O. Santos^a and M.D. Wigg^a, , 

^aDepartamento de Virologia, Instituto de Microbiologia Professor Paulo de Góes, Universidade Federal do Rio de Janeiro Centro de Ciências da Saúde (CCS), Bloco I, Caixa Postal 68040, CEP 21941-590, Rio de Janeiro, Brazil

^bInstituto de Biologia, Departamento de Botânica, Universidade Federal do Rio de Janeiro, CEP 21941-590, Rio de Janeiro, Brazil

^cNúcleo de Pesquisas de Produtos Naturais, Universidade Federal do Rio de Janeiro, CEP 21941-590, Rio de Janeiro, Brazil

Received 28 December 2004;   revised 28 December 2004;  accepted 14 January 2005.   Available online 3 May 2005. 

Abstract

Acute diarrhea, especially in children, is a very common disease with worldwide distribution and with a significant public health impact. Rotaviruses have been recognized as the major agents of diarrhea in infants and young children in developed as well as developing countries. In Brazil, diarrhea is one of the principal causes of death, mainly in the infant population. To fight diarrhea, traditional Brazilian medicine uses a great variety of plants. In this work, 12 medicinal plant species were screened for simian (SA-11) and human (HCR3) rotaviruses inhibition in vitro. At non-cytotoxic concentrations, the extracts from Artocarpus integrifolia L. (Moraceae) bark (480 μg/ml) and Spondias lutea L. (Anacardiaceae) leaves (160 μg/ml) had antiviral activity against both viruses. They showed inhibition of 99.2% and 97%, respectively, for human rotavirus, and 96.4% and 96.2% for simian rotavirus. The extracts from Myristica fragrans Houtt (Myristicaceae) seeds (160 μg/ml) and Spongias lutea bark (40 μg/ml) inhibited human rotavirus (90% and 82.2% inhibition, respectively), whereas the extracts from Anacardium occidentale L. (Anacardiaceae) leaves (4 μg/ml) and Psidium guajavaL. (Myrtaceae) leaves (8 μg/ml) showed activity only against simian rotavirus (82.2% and 93.8% inhibition, respectively). Our results indicate that the extracts of Artocarpus integrifolia, Myristica fragrans and Spongias lutea can be useful in the treatment of human diarrhea if the etiologic agent is a rotavirus.

Keywords: Antiviral activity; Rotavirus; Cytotoxicity; MA-104 cells; Diarrhea; Plant extracts